PLAU 抗体
Quick Overview for PLAU 抗体 (ABIN7117556)
抗原
See all PLAU 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PLAU antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- plasminogen activator, urokinase
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IHC:1:20-1:200,IF: 1:20-1:200, IP: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PLAU (Plasminogen Activator, Urokinase (PLAU))
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别名
- PLAU
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背景
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Synonyms: Urokinase-type plasminogen activator (U-plasminogen activator, uPA)|Urokinase-type plasminogen activator long chain A|Urokinase-type plasminogen activator short chain A|Urokinase-type plasminogen activator chain B|PLAU
Background: PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1(PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder(QPD).
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分子量
- 54 kDa
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基因ID
- 5328
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UniProt
- P00749
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途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
抗原
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